Hypoglycemia and Insular Hyperplasia
نویسندگان
چکیده
منابع مشابه
Quantifying Insulin Sensitivity and Entero-Insular Responsiveness to Hyper- and Hypoglycemia in Ferrets
Ferrets are an important emerging model of cystic fibrosis related diabetes. However, there is little documented experience in the use of advanced techniques to quantify aspects of diabetes pathophysiology in the ferret. Glycemic clamps are the gold standard technique to assess both insulin sensitivity and insulin secretion in humans and animal models of diabetes. We therefore sought to develop...
متن کاملInsular Cortex and Insular Epilepsy
Insular cortex epilepsy is an under-recognized, localization-related syndrome. The presence of this condition could account for the surgery treatment failure seen in a portion of patients with temporal epilepsy, as well as a portion of those with frontal and parietal lobe epilepsy. Most cases of intractable temporal epilepsy are associated with insular cortex involvement. In this review, we wil...
متن کاملCortisol responsiveness to insulin-induced hypoglycemia in Cushing's syndrome with huge nodular adrenocortical hyperplasia.
A 51-yr-old male patient with a 3 yr history of Cushing's syndrome is described. The baseline plasma cortisol level was elevated, while the plasma ACTH levels remained at an undetectable level. Dynamic testing of pituitary-adrenal function revealed no suppression after 8 mg of dexamethasone, and there was no response to metyrapone or CRF, while plasma cortisol showed a hyperresponse to syntheti...
متن کاملOverexpression of cyclin D1 in pancreatic beta-cells in vivo results in islet hyperplasia without hypoglycemia.
Cyclin D1 can stimulate proliferation by driving cells from the G1 into the S-phase of the mammalian cell cycle. Previous animal studies have implicated the G1-S transition as a key regulatory checkpoint governing the proliferation of pancreatic islet cells. We expressed cyclin D1 in the beta-cells of mice and islet hyperplasia developed in a time-dependent manner. The hyperplastic beta-cells e...
متن کاملInsular microbiogeography
James H. Kaufman Christopher A. Elkins Matthew Davis Allison M. Weis Bihua C. Huang Mark K. Mammel Isha Patel Kristen L. Beck Stefan Edlund David Chambliss Simone Bianco <s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1974
ISSN: 0003-4932
DOI: 10.1097/00000658-197407000-00020